The Neuronal Oscillations Research Group

Brain oscillations in cognition and disorders

The 'Neuronal Oscillations' research group is part of the newly established Centre for Human Brain Health at University of Birmingham. It is headed by Prof. Ole Jensen, Wolfson Research Merit Award holder. The main goal of the Neuronal Oscillations research group is to understand how oscillatory activity shapes the functional architecture of the working brain during cognitive processing. While modulations of alpha band oscillations (8-13 Hz) reflect anticipatory top-down modulation, bottom-up processing is reflected by gamma band synchronization (30-100 Hz). Specifically, our core hypothesize states that neuronal communication is gated by inhibitory alpha oscillations in task-irrelevant regions, thus routing information to task-relevant regions. According to this framework the brain can be studied as a network by investigating cross-frequency interactions between gamma and alpha activity. The research tools applied by the group include computational modeling, MEG, EEG combined with fMRI, EEG combined with TMS and intracranial recordings. We are also developing optically pumped magnetometers (OPMs). These tools are applied to investigate and interpret data from humans and animals performing attention and memory tasks. Furthermore, we investigate these mechanism to understand the basis of attention problems in ADHD patients and the aging population. The group is funded by a Wellcome Trust Senior Investigator award, the James S. McDonnell Foundation, the BBSRC, The Templeton Foundation and several EU Horizon 2020 Marie Curie fellowships.


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